There is only one place in America where two of our nation’s great roadways come together alongside the confluence of America’s three great rivers. And that is right here in the Great Rivers and Routes region of Southwest Illinois. Journey down historic Route 66 from Virden to just outside St. Louis to meet the miners, mobsters and characters that infuse the small towns along the way. Then hop on to the Meeting of the Great Rivers National Scenic Byway to experience the majesty of the confluence of the Missouri, Mississippi and Illinois rivers. Begin your celebration of America’s great roads and rivers today!