Hotels & Motels
Where to Stay
After a long day of exploring the Great Rivers & Routes region, you’re going to want a place to relax and rest up before your next adventure.
The area has more than 40 full-service and limited service hotels, motels and other lodging options with a total of 3,100 rooms available.
Lodging in the region ranges from high-end hotel stays to camping and RV sites surrounded by Mother Nature.
Want a more personal experience? We’ve got a number of bed & breakfast spots waiting for you.
Aiming to stay a little longer? Vacation rentals dot the banks of the Mississippi River, especially in Grafton and Alton.
Browse our lodging listings for the complete roundup of hotels, cabins and more.
Bed & Breakfasts
Vacation Rentals
Camping & RVs
14 W Main Street
Grafton, Illinois 62037
(618) 786-8439
Website
The Deckhouse at Aerie's Resort14 W Main Street
Grafton, Illinois 62037
1446 West Main
Grafton, Illinois 62037
(618) 786-7378
Website
Dee's Riverside Retreat1446 West Main
Grafton, Illinois 62037
300 Water St.
Grafton, Illinois 62037
(618) 410-1767
Website
DeSherlia Landing Suites300 Water St.
Grafton, Illinois 62037
200 South Front Street
East St. Louis, Illinois 62201
1-800-777-0777
Website
DraftKings at Casino Queen RV Park200 South Front Street
East St. Louis, Illinois 62201
602 N. Bluff Rd.
Collinsville, Illinois 62234
(618) 345-7700
Website
Drury Inn & Suites St. Louis Collinsville602 N. Bluff Rd.
Collinsville, Illinois 62234
105 E. Main Street
Grafton, Illinois 62037
(618) 550-8505
Website
End of the Trail Inn105 E. Main Street
Grafton, Illinois 62037
4 Gateway Dr.
Collinsville, Illinois 62234
(618) 346-0607
Website
Fairfield by Marriott Collinsville4 Gateway Dr.
Collinsville, Illinois 62234
5224 Commerce Parkway
Pontoon Beach, Illinois 62040
(618) 709-7933
Website
Fairfield Inn & Suites St. Louis Pontoon Beach/ Granite City, IL5224 Commerce Parkway
Pontoon Beach, Illinois 62040
506 N. Main St.
Carrollton, Illinois 62016
(217) 718-2999
Website
The Farmhouse Loft506 N. Main St.
Carrollton, Illinois 62016
Grafton, Illinois 62037
(618) 946-6077
Website
Fisch Houz - GraftonGrafton, Illinois 62037
1106 - 1110 George St.
Alton, Illinois 62002
(618) 433-9403
Website
George Street Suites1106 - 1110 George St.
Alton, Illinois 62002
210 W. Main St.
Grafton, Illinois 62037
(217) 742-2226
Website
Gold Nugget210 W. Main St.
Grafton, Illinois 62037
26204 Lakeview Terrace
Godfrey, Illinois 62035
(314) 662-1837
Website
Grafton Getaway - Overlook Lodge26204 Lakeview Terrace
Godfrey, Illinois 62035
20806 Croxford Road, Croxford Road to the Homestead sign
Grafton, Illinois 62037
(618) 786-2420
Website
Find A Room
Grafton Homestead Retreat20806 Croxford Road, Croxford Road to the Homestead sign
Grafton, Illinois 62037
22 E. Main Street
Grafton, Illinois 62037
(618) 786-2222
Website
Grafton Inn22 E. Main Street
Grafton, Illinois 62037
100 N. Springfield St.
Grafton, Illinois 62037
(618) 558-6891
Website
Grafton Stone Cottage100 N. Springfield St.
Grafton, Illinois 62037
300 Pelican Way
Grafton, Illinois 62037
(217) 823-6800
Website
The Gray Pelican300 Pelican Way
Grafton, Illinois 62037
617 State Street
Alton, Illinois 62002
(618) 444-7969
Haagen Haus617 State Street
Alton, Illinois 62002
1904 Homer M. Adams Parkway
Alton, Illinois 62002
(618) 433-8999
Website
Hampton Inn & Suites by Hilton Alton1904 Homer M. Adams Parkway
Alton, Illinois 62002
5723 Heritage Crossing Dr.
Glen Carbon, Illinois 62034
(618) 589-5000
Website
Hampton Inn & Suites St Louis - Edwardsville5723 Heritage Crossing Dr.
Glen Carbon, Illinois 62034
11 Thunderbird Circle
Litchfield, Illinois 62056
(217) 324-4441
Website
Hampton Inn Litchfield11 Thunderbird Circle
Litchfield, Illinois 62056
10236 393rd St
Nebo, Illinois 62355
(217) 734-2526
Website
Harpole's Heartland Lodge10236 393rd St
Nebo, Illinois 62355
10236 393rd St.
Nebo, Illinois 62355
(800) 717-4868
Website
Harpole's Heartland Lodge/Heavenly View Cabin10236 393rd St.
Nebo, Illinois 62355
203 Mulberry St.
Grafton, Illinois 62037
(618) 946-7509
Heaven's Gate203 Mulberry St.
Grafton, Illinois 62037