Hotels & Motels
Where to Stay
After a long day of exploring the Great Rivers & Routes region, you’re going to want a place to relax and rest up before your next adventure.
The area has more than 40 full-service and limited service hotels, motels and other lodging options with a total of 3,100 rooms available.
Lodging in the region ranges from high-end hotel stays to camping and RV sites surrounded by Mother Nature.
Want a more personal experience? We’ve got a number of bed & breakfast spots waiting for you.
Aiming to stay a little longer? Vacation rentals dot the banks of the Mississippi River, especially in Grafton and Alton.
Browse our lodging listings for the complete roundup of hotels, cabins and more.
Bed & Breakfasts
Vacation Rentals
Camping & RVs
1446 West Main
Grafton, Illinois 62037
(618) 786-7378
Website
Dee's Riverside Retreat1446 West Main
Grafton, Illinois 62037
300 Water St.
Grafton, Illinois 62037
(618) 410-1767
Website
DeSherlia Landing Suites300 Water St.
Grafton, Illinois 62037
200 South Front Street
East St. Louis, Illinois 62201
1-800-777-0777
Website
DraftKings at Casino Queen RV Park200 South Front Street
East St. Louis, Illinois 62201
602 N. Bluff Rd.
Collinsville, Illinois 62234
(618) 345-7700
Website
Drury Inn & Suites St. Louis Collinsville602 N. Bluff Rd.
Collinsville, Illinois 62234
105 E. Main Street
Grafton, Illinois 62037
(618) 550-8505
Website
End of the Trail Inn105 E. Main Street
Grafton, Illinois 62037
4 Gateway Dr.
Collinsville, Illinois 62234
(618) 346-0607
Website
Fairfield by Marriott Collinsville4 Gateway Dr.
Collinsville, Illinois 62234
5224 Commerce Parkway
Pontoon Beach, Illinois 62040
(618) 709-7933
Website
Fairfield Inn & Suites St. Louis Pontoon Beach/ Granite City, IL5224 Commerce Parkway
Pontoon Beach, Illinois 62040
506 N. Main St.
Carrollton, Illinois 62016
(217) 718-2999
Website
The Farmhouse Loft506 N. Main St.
Carrollton, Illinois 62016
1106 - 1110 George St.
Alton, Illinois 62002
(618) 433-9403
Website
George Street Suites1106 - 1110 George St.
Alton, Illinois 62002
210 W. Main St.
Grafton, Illinois 62037
(217) 742-2226
Website
Gold Nugget210 W. Main St.
Grafton, Illinois 62037
26204 Lakeview Terrace
Godfrey, Illinois 62035
(314) 662-1837
Website
Grafton Getaway - Overlook Lodge26204 Lakeview Terrace
Godfrey, Illinois 62035
20806 Croxford Road, Croxford Road to the Homestead sign
Grafton, Illinois 62037
(618) 786-2420
Website
Find A Room
Grafton Homestead Retreat20806 Croxford Road, Croxford Road to the Homestead sign
Grafton, Illinois 62037
22 E. Main Street
Grafton, Illinois 62037
(618) 786-2222
Website
Grafton Inn22 E. Main Street
Grafton, Illinois 62037
300 Pelican Way
Grafton, Illinois 62037
(217) 823-6800
Website
The Gray Pelican300 Pelican Way
Grafton, Illinois 62037
503 N. Main St.
White Hall, Illinois 62092
Website
Greene Gables Inn503 N. Main St.
White Hall, Illinois 62092
617 State Street
Alton, Illinois 62002
(618) 444-7969
Haagen Haus617 State Street
Alton, Illinois 62002
1904 Homer M. Adams Parkway
Alton, Illinois 62002
(618) 433-8999
Website
Hampton Inn & Suites by Hilton Alton1904 Homer M. Adams Parkway
Alton, Illinois 62002
5723 Heritage Crossing Dr.
Glen Carbon, Illinois 62034
(618) 589-5000
Website
Hampton Inn & Suites St Louis - Edwardsville5723 Heritage Crossing Dr.
Glen Carbon, Illinois 62034
11 Thunderbird Circle
Litchfield, Illinois 62056
(217) 324-4441
Website
Hampton Inn Litchfield11 Thunderbird Circle
Litchfield, Illinois 62056
10236 393rd St.
Nebo, Illinois 62355
(800) 717-4868
Website
Harpole's Heartland Lodge/Heavenly View Cabin10236 393rd St.
Nebo, Illinois 62355
203 Mulberry St.
Grafton, Illinois 62037
(618) 946-7509
Heaven's Gate203 Mulberry St.
Grafton, Illinois 62037
202 W. Main St.
Grafton, Illinois 62037
(618) 604-4513
Website
Hilltop202 W. Main St.
Grafton, Illinois 62037
123 E Seward St
Hillsboro, Illinois 62049
Website
The Historic Red Rooster Inn123 E Seward St
Hillsboro, Illinois 62049
1000 Plummer Dr.
Edwardsville, Illinois 62025
(618) 692-7255
Website
Holiday Inn Express & Suites Edwardsville1000 Plummer Dr.
Edwardsville, Illinois 62025