Hotels & Motels
Where to Stay
After a long day of exploring the Great Rivers & Routes region, you’re going to want a place to relax and rest up before your next adventure.
The area has more than 40 full-service and limited service hotels, motels and other lodging options with a total of 3,100 rooms available.
Lodging in the region ranges from high-end hotel stays to camping and RV sites surrounded by Mother Nature.
Want a more personal experience? We’ve got a number of bed & breakfast spots waiting for you.
Aiming to stay a little longer? Vacation rentals dot the banks of the Mississippi River, especially in Grafton and Alton.
Browse our lodging listings for the complete roundup of hotels, cabins and more.
Bed & Breakfasts
Vacation Rentals
Camping & RVs
801 S. Neunaber Drive
Bethalto, Illinois 62010
(618) 377-3474
Website
Town & Country Lakes801 S. Neunaber Drive
Bethalto, Illinois 62010
6101 Center Grove Road
Edwardsville, Illinois 62025
(618) 655-3001
Website
TownePlace Suites By Marriott-St. Louis Edwardsville6101 Center Grove Road
Edwardsville, Illinois 62025
201 N 2nd Street
Edwardsville, Illinois 62025
(618) 659-9506
Website
Urban Collective Boutique Hotel201 N 2nd Street
Edwardsville, Illinois 62025
210 W. Oak St.
Kampsville, Illinois 62053
(618) 653-4421
Village of Kampsville Campground210 W. Oak St.
Kampsville, Illinois 62053
592 Crawford Creek Rd.
Kampsville, Illinois 62053
(618) 653-4687
Website
Watkins House at McCully Heritage Project592 Crawford Creek Rd.
Kampsville, Illinois 62053
202 W. Main St.
Grafton, Illinois 62037
(314) 934-5260
Website
White Lotus202 W. Main St.
Grafton, Illinois 62037