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Hotels
After a long day of exploring the Great Rivers & Routes region, you’re going to want a place to relax and rest up before your next adventure.
Lodging in the region ranges from high-end hotel stays to camping and RV sites surrounded by Mother Nature. The area has more than 40 full-service and limited service hotels, motels and other lodging options with a total of 3,100 rooms available.
Want a more personal experience? We’ve got a number of bed & breakfast spots waiting for you.
Aiming to stay a little longer? Vacation rentals dot the banks of the Mississippi River, especially in Grafton and Alton.
Browse our lodging listings for the complete roundup of hotels, cabins and more.
Bed & Breakfasts
An elegant and award-winning mansion, a blufftop retreat overlooking the Mississippi River and a...
Camping/RV
Some spots in the Great Rivers & Routes region are BYOB – bring your own bed. Whether...