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Hotels

After a long day of exploring the Great Rivers & Routes region, you’re going to want a place to relax and rest up before your next adventure.

Lodging in the region ranges from high-end hotel stays to camping and RV sites surrounded by Mother Nature. The area has more than 40 full-service and limited service hotels, motels and other lodging options with a total of 3,100 rooms available.

Want a more personal experience? We’ve got a number of bed & breakfast spots waiting for you.

Aiming to stay a little longer? Vacation rentals dot the banks of the Mississippi River, especially in Grafton and Alton.

Browse our lodging listings for the complete roundup of hotels, cabins and more.

Spring

Spring is finally here and nature is alive at last! Blades of luscious green grass are dancing...

Summer

Get away to the Meeting of the Great Rivers National Scenic Byway all around Alton, Illinois for...

Fall

From beautiful fall color drives to a jaunt out into the apple orchard, an authentic autumn...

Haunted

Alton, this quaint river town, has become known as "One of the Most Haunted Small Towns in...

Holiday

Get into the holiday spirit with these chart-toppers that make the season bright at the Meeting of...

Eagle

Just 25 miles north of St. Louis on the Mississippi River, Alton, Ill., has become a winter home to...